GUANIDINE STRUCTURE AND HYPOGLYCEMIA

Guanidine Structure and Hypoglycemia

By a series of structural changes, Frank, Nothmann, and Wagner (1) developed synthalin, the most powerful hypoglycemic synthetic product known today. The details of their researches are not available. The increased hypoglycemic activity of agmatine over guanidine offered the first clue as to the nature of the groups which were productive of hypoglycemic activity. It may be gathered from the rec...

The Structure of the Guanidine-II Riboswitch

The guanidine-II (mini-ykkC) riboswitch is the smallest of the guanidine-responsive riboswitches, comprising two stem loops of similar sequence. We have solved high-resolution crystal structures of both stem loops for the riboswitch from Gloeobacter violaceus. The stem loops have a strong propensity to dimerize by intimate loop-loop interaction. The dimerization creates specific binding pockets...

Structure of the Guanidine III Riboswitch

Riboswitches are structural elements found in mRNA molecules that couple small-molecule binding to regulation of gene expression, usually by controlling transcription or translation. We have determined high-resolution crystal structures of the ykkC guanidine III riboswitch from Thermobifida fusca. The riboswitch forms a classic H-type pseudoknot that includes a triple helix that is continuous w...

Guanidine ferridehemoglobin and the carbimid structure of cyanamide; the relationship of chemical structure to cholinergic activity.

the underlying structure of language proficiency and the proficiency level

هدف از انجام این تخقیق بررسی رابطه احتمالی بین سطح مهارت زبان خارجی (foreign language proficiency) و ساختار مهارت زبان خارجی بود. تعداد 314 زبان آموز مونث و مذکر که عمدتا دانشجویان رشته های زبان انگلیسی در سطوح کارشناسی و کارشناسی ارشد بودند در این تحقیق شرکت کردند. از لحاظ سطح مهارت زبان خارجی شرکت کنندگان بسیار با هم متفاوت بودند، (75 نفر سطح پیشرفته، 113 نفر سطح متوسط، 126 سطح مقدماتی). کلا ...